• Jim Appleyard
  • Michel Botbol



attunement, biopsychosocial, adverse child event, allostatic, empathy, cumulative and programming events


Health is a consequence of multiple determinants operating in interrelated genetic, biological, behavioral, social, and economic contexts that change as a person develops.The timing and sequence of such events and experiences influence the health and development of both individuals and populations. A life course perspective offers a more joined up approach with significant implications for long term health gain. A three-dimensional picture needs to evolve laterally in the present, longitudinally from earlier life events and likely future projections, and vertically from the advances in the medical sciences.


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